為了監測嗎啉甲基化法生成N-甲基嗎啉反應的收率,浩瀚色譜（山東）應用技術開發有限公司應用氣相色譜建立了一套用N-甲基吡咯烷酮作為內標物,程序升溫測定N-甲基嗎啉質量分數的方法。該方法主要依托于GC-氣相色譜,其檢測器為氫火焰離子檢測器,載氣為氮氣,色譜柱為HH-5毛細管柱(規格30 m×0.32 mm×0.5UMμm)。通過回收率和重復性的測定,驗證了該方法準確度和精密度均較高,能夠準確測定混合液中N-甲基嗎啉的含量。

N-甲基嗎啉測定毛細管柱 測試譜圖：



Capillary column for N-methylmorpholine determination
N-Methylmorpholine Determination Capillary Column Details:

Name: capillary column
Stationary phase: 5% phenyl-methyl polysiloxane
Specifications: 30m*0.32mm*0.5um
Model: HH-5
Application: Gas Chromatographic Analysis of N-Methylmorpholine

Due to the special molecular structure and physical properties of N-formylmorpholine, its new application fields are constantly being developed. In addition to extractive distillation to recover and refine aromatic hydrocarbons, morpholine derivatives have recently been found to have good gas desulfurization efficiency, high quality of purified gas, low operating costs and low investment in the process.

In order to monitor the yield of the reaction of morpholine methylation to N-methylmorpholine, Haohan Chromatography (Shandong) Application Technology Development Co., Ltd. applied gas chromatography to establish a set of temperature-programmed determinations using N-methylpyrrolidone as an internal standard. Method for mass fraction of N-methylmorpholine. The method mainly relies on GC- gas chromatography, the detector is hydrogen flame ion detector, the carrier gas is nitrogen, and the chromatographic column is HH-5 capillary column (30 m×0.32 mm×0.5UMμm). Through the determination of recovery rate and repeatability, it is verified that the method has high accuracy and precision, and can accurately determine the content of N-methylmorpholine in the mixture.


N-Methylmorpholine Determination Capillary Column Test Spectrum: